one of my current struggles with swinging is the proper swivel or dual horizontal hinge action.
I am trying different wrist actions to match my pivot actions.
I notice that my rhythm is bang on when I employ standard wrist action as the rate which I turn zone 1 muscles is at the same rpm as the rolling of my left wrist.
I think that is one of the difficulties with swinging is not to compensate too much and feel the pressure points just exclusively with PP#4 or PP#2 but both.
Check your grip at impact fix. It sounds like the hands are working too hard for clubface control - they are clamps - and the proper alignments at impact fix are the only sure way to allow them to act like clamps!
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I actually feel the activation of the thenar muscles during impact fix. This gives me more precise alignments at address.
Non adjusted address such a lagging clubhead takeaway is when my hands feels more like clamps and the thenar muscles tighten up during the takeaway.